A 4-month-old girl who was born full-term presents to her pediatrician with an upper respiratory infection. Her mother notes that this is the fifth time her daughter has had an upper respiratory infection since birth. Her past medical history is significant for seizures shortly after birth. In addition to pulmonary findings, the physical examination is notable for oropharyngeal candidiasis that the patient’s mother says has been occurring regularly. This child is presenting with a syndrome that is due to aberrant development of which of the following embryonic structures?
- (A) First and second branchial arches
- (B) First and second branchial pouches
- © Fourth and sixth branchial arches
- (D) Second and third branchial clefts
- (E) Third and fourth branchial pouches
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A 21-year-old man presents to a new primary care physician for routine physical examination. He demonstrates hyperextensible skin and reports a history of finger and shoulder dislocations, which he has reduced himself. He reports a history of easy bruising. He has no cardiac abnormalities. A defect in the synthesis of which molecule likely accounts for these symptoms?
- (A) Collagen type I
- (B) Collagen type II
- © Collagen type III
- (D) Collagen type IV
- (E) Elastin
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