A 55 year old post menopausal woman

NEET PG Surgery
#1

A 55 year old post menopausal woman, on hormone replacement therapy (HRT), presents with heaviness in both breasts. A screening mammogram reveals a high density speculated mass with cluster of pleomorphic microcalcification and ipsilateral large axillary lymph nodes. The mass described here most likely represents -

    1. Cystosarcoma phylloides
    1. Lymphoma
    1. Fibroadenoma
    1. Carcinoma

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exp:

  • H/O of hormone replacement therapy and characteristic features on mammogram confirm the diagnosis of Breast carcinoma
  • Mammographic findings of high density, speculated mass with clusters of pleomorphic micro calcification correlate with carcinoma breast.

Note : In hormone replacement therapy estrogen is given and its use has been associated with these risks

  1. Predisposition to breast carcinoma
  2. Gallstones
  3. Worsening of migraine