A 71-year-old woman with a medical history of obesity and diabetes mellitus present to your clinic com-
plaining of right knee pain that has been progressive and
is worse with walking or standing. She has taken over-
the-counter nonsteroidal anti-inflammatory drugs with-
out relief. She wants to know what is wrong with her knee
and what may have caused it. X-rays are performed and
reveal cartilage loss and osteophyte formation. Which of
the following represents the most potent risk factor for
the development of osteoarthritis?
- A. Age
- B. Gender
- C. Genetic susceptibility
- D. Obesity
- E. Previous joint injury
A. Osteoarthritis has always been called “age related wear and tear” and age is the strongest risk factor. If you check UpToDate “Age is one of the strongest predictors of OA”. The others are RFs but age is the strongest RF for sure.