A blood film shows target cells and Howell-Jolly bodies. What is the most likely cause of the anaemia?


#1

A 20-year-old pregnant lady is found to be anaemic at 10 weeks gestation. A full blood count is ordered:

Hb=85 g/L
MCV=95 fL

The lab also reports a high reticulocyte count. A blood film shows target cells and Howell-Jolly bodies. What is the most likely cause of the anaemia?

A. Folate deficiency
B. Anaemia of chronic disease
C. Iron deficiency
D. B12 deficiency
E. Sickle cell disease

Ans:

E. Sickle cell disease