A patient is being discharged from the hospital on a 3-week course of clindamycin. Which of the following potential adverse effects should be discussed with her?
C. Clostridium difficile diarrhea.
D. Pseudotumor cerebri.
Correct answer = C.
Clindamycin, among other antibiotics, is associated with the development of C. difficile and pseudomembranous colitis due to disruption of normal gut flora, particularly with prolonged therapy. Hyperbilirubinemia is associated with quinupristin/dalfopristin, nephrotoxicity is associated with aminoglycosides, and pseudotumor cerebri
can occur with tetracyclines.
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