Agents which decrease bone resorption in osteoporosis – Orthopaedics MCQ

Agents which decrease bone resorption in osteoporosis are all except?

A. Risedronate
B. Teriparatide
C. Strontium ranelate
D. Raloxifene

Correct answer : B. Teriparatide

osteoporotic fracture

X-ray spine – lateral view – showing osteoporotic wedge fractures of vertebrae – L1 & L2

Drugs used for treatment of osteoporosis
:black_medium_small_square:Drugs which reduce bone resorption (anti resorptive drugs):black_medium_small_square:Selective estrogen receptor modulators – Raloxifene
:black_medium_small_square:Bisphosphonates – Etidronate, Risedronate, Pamidronate, Alendronate
:black_medium_small_square:Hormone replacement therapy / estrogen
:black_medium_small_square:Calcitonin
:black_medium_small_square:Calcium supplements
:black_medium_small_square:Vitamin D
:black_medium_small_square:Denosumab -Monoclonal antibody which inhibits the maturation of osteoclasts by binding to and inhibiting RANKL.

:black_medium_small_square:Drugs which increase bone formation​:black_medium_small_square:Teriparatide

:black_medium_small_square:Drugs with both effects (decreases bone resorption and increases bone formation):black_medium_small_square:Strontium ranelate