Alagille syndrome is a genetic disorder

Alagille syndrome is a genetic disorder that can affect the liver, heart, and other parts of the body. One of the major features of Alagille syndrome is liver damage caused by abnormalities in the bile ducts. These ducts carry bile (which helps to digest fats) from the liver to the gallbladder and small intestine.


Symptoms of Alagille Syndrome are

》 jaundice;

》 pale,

》 loose stools; and

》 poor growth within the first three

months of life.

Later, there is persistent jaundice, itching, fatty deposits in the skin, and #stunted growth and development during early childhood.


diagnose Alagille syndrome based on signs and symptoms, medical and #family_history, a #physical_exam, an eye exam, and medical tests, which may include blood tests, imaging tests, and a liver #biopsy.


While there is no known cure for Alagille syndrome, there are treatments that can help control symptoms. Possible treatments may include #medication_that_increases the flow of bile and careful management of diet to minimize nutrition and vitamin related problems. In severe cases, a liver transplant may be necessary.

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