Alagille syndrome is which pathway defect? NOTCH 1 or NOTCH 2?
In Ed 5 videos and notes you mentioned NOTCH 2 but in Med80 you mentioned NOTCH 1. Which option to follow? Please guide.
Jag 1 notch 2 liver manifestations
Notch 1 cardiac manifestations
Of alagille syndrome
Notch 3 CADASIL
Just imagine the responsibility of a treating doctor with this example…even a small error that too partial can finish u in d court of law…there saying sorry just wouldn’t work…b shaaaaarp
mutations in the JAG1 gene responsible for Alagille syndrome in more than 90 percent of patients and only a small percentage have mutations in the NOTCH2 gene.