An elderly pt with poorly controlled T2DM (HbA1C 60mmol/mol) with a H/O hypoglycemia with SNUs

An elderly pt with poorly controlled T2DM (HbA1C 60mmol/mol) with a H/O hypoglycemia with SNUs.
She lives alone and currently taking metformin, ramipril, lansoprazole and amlodipine. Her comorbidities include hypertension, hiatus hernia and OA. Her BMI 42. She does not wish to have injectable therapy.

Which of the following agents would be most appropriate ?

  1. Exenatide
  2. Glimepride
  3. Pioglitazone
  4. Repaglinide
  5. Sitagliptin

20 Comments