Bacterial infection due to a contaminated blood product is most likely with transfusion of

NEET PG Anaesthesia
#1

Bacterial infection due to a contaminated blood product is most likely with transfusion of

  1. Packed red blood cells

  2. Fresh-frozen plasma

  3. Platelets

  4. Cryoprecipitate

solution

One of the leading causes of transfusion-related fatalities in the United States is bacterial contamination, which is most likely to occur in platelet concentrates. Platelet-related sepsis can be fatal and occurs as frequently as 1 in 5,000 transfusions. Platelets are stored at 20 to 24°C instead of 4°C, which probably accounts for the greater risk of bacterial growth than with other blood products. Any patient in whom a fever develops within 6 hours of receiving platelet concentrates should be considered to be possibly manifesting platelet-induced sepsis, and empirical antibiotic therapy should be instituted.