Characteristic feature of apoptosis -

Characteristic feature of apoptosis -

  1. Cell membrane intact

  2. Cytoplasmic eosinophilia

  3. Nuclear moulding

  4. Cell swelling

Explanation:

  • No option is exactly correct in this question, as chromatin condensation is the most characteristic feature of apoptosis.
  • But, we have to choose one option anyways.
  • Amongst the given options two features are seen in apoptosis : -

Option a → Cell membrane intact

Option b → Cytoplasmic eosinophilia

  • Cytoplasmic eosinophilia is not characteristic feature of apoptosis; cytoplasmic eosinophilia is also seen in necrosis.

  • On the other hand Intact cell membrane is a striking feature of apoptosis and it differentiates apoptosis from necrosis (in which cell membrane is damaged)

  • Mast characteristic feature of apoptosis → Chromatin condensation (Fyknosis)

  • Earliest change of apoptosis → Cell shrinkage

  • End stage of apoptosis → Formation of cytoplasmic blebs & apoptotic bodies.

  • Most striking feature of apoptosis → Absence of inflammation.