During an assessment of a neonate born at 33 weeks’ gestation

During an assessment of a neonate born at

33 weeks’ gestation, a nurse fi nds and reports a heart

murmur. An echocardiogram reveals patent ductus

arteriosis, for which the neonate received indomethacin.

An expected outcome after the administration

of indomethacin to a neonate with patent

ductus arteriosis is:

■ 1. Closure of a patent ductus arteriosus.

■ 2. Decreased bleeding time.

■ 3. Increased gastrointestinal function.

■ 4. Increased renal output.

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  1. The indication for the use of indomethacin

is to close a patent ductus arteriosus. Adverse

effects include decreased renal blood fl ow, platelet

dysfunction with coagulation defects, decreased GI

motility, and an increase in necrotizing enterocolitis.

Thus, increased bleeding time, decreased gastrointestinal

function, and decreased renal output

would be expected outcomes after the administration

of indomethacin.