Exclude myasthenia gravis >>> if upper motor neurone or sensory lesion

Exclude myasthenia gravis >>> if upper motor neurone or sensory lesion …It is pure lower motor neurone.

Guillaume Barre >>>with any upper motor neurone signs ( extensor plantar - hyperreflexia) …It is only lower neurone ( motor and sensory).

Exclude motor neurone disease or amytrophic lateral sclerosis >>> in case of any lower motor neurone or sensory lesion …It is UMN lesion only .

Exclude conus medullaris >>> in knee reflex is lost …Both knee and ankle are lost in cauda equina lesion .

Exclude lateral medullary syndrome>>>> if any pyramidal signs ( hemiparesis or ext plantar reflex).

Do not forget …reflexes are lost with GB syndrome or its variant ( Miller Fischer) , but preserved with mayasthenia .