False about Pseudomyoxma peritonei is
a) Recurrence after surgery
b) Refractory to drugs
c) Hyperthermic intraperitoneal chemotherapy is treatment option
d) Most commonly associated with appendiceal tumour
Ans: B Reference: Sabiston 20th ed; pg. 1080 & Bailey 27th ed; pg. 1316 Explanation:
• Pseudomyxoma peritonei is a rare condition which describes mucinous ascites arising from a ruptured ovarian or appendiceal carcinoma. • First described by Fraenkel, condition typically has progressive peritoneal tumor deposits, mucinous ascites, omental cake and ovarian involvement in females • Most commonly associated with appendiceal tumor • Occurs most commonly in patients who are 40 to 50 years of age and occurs in equal frequency in both males and females • Risk of developing pseudomyxoma peritonei following removal of appendix harbouring epithelial tumor is 9%, non mucinous neoplasm is 3% and 30% with mucinous adenocarcinoma • Current accepted treatment is Cytoreductive surgery with Heated or Hyperthemia Intra Peritoneal Chemotherapy (CRS + HIPEC) which includes omentectomy, stripping of involved peritoneum, resection of involved organs and appendicectomy. • The survival rates after CRS + HIPEC increased from 20 to 30% to 55% nowadays.