Fibrin ring granuloma/ doughnut granuloma


#1

Fibrin ring granuloma/ doughnut granuloma

:four_leaf_clover:It is a histopathological finding that is characteristic of Q fever caused by coxiella burnetii.

:cherry_blossom:On H and Estaining, the fibrin ring granuloma consists of a central lipid vacuole (usually washed-out during fixing and staining, leaving only an empty hole) surrounded by a dense red fibrin ring and epithelioid macrophages.(resembles like doughnut)

:blossom:It may also be seen in Hodgkin’s Lymphoma and infectious mononucleosis.