Growth hormone deficiency (GHD) is noted in which of the following?
Chronic renal failure (CRF) Incorrect answer selected
Constitutional short stature
Laron’s syndrome
Sheehan’s syndrome This is the correct answer
Turner’s syndrome
Sheehan’s syndrome is post-delivery infarction of the pituitary and growth hormone deficiency is
typical.
Although GH therapy is used in CRF, Turner’s syndrome and short stature subjects are not GH
deficient.
Laron’s syndrome is due to a GH receptor defect with impaired IGF-1 production. It is an autosomal
recessive condition, characterised by short stature and reduced incidence of cancer and diabetes