IgE is secreted by -
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- Mast cell
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- Basophils
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- Eosinophils
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- Plasma cells
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- Neutrophils
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exp:
Plasma cells
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Plasma cells are the antibody secreting cells
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On contact with its appropriate antigen, the mature B cell undergoes clonal proliferation. The majority of activated B cells are transformed into plasma cells and secrete antibodies.
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Plasma cells make an antibody of a single specificity, of ci single immunoglobulin class and allotype,and of a single light chain type only. An exception is seen in the primary antibody response, when a plasma cell producing Ig M initially, may later be switched to Ig G production.
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While plasma cell is the best antibody producing cell, lymphocytes, lymphoblasts and transitional cells may also synthesise Ig to some extent.