In a male with Addison’s disease, what forms of treatment are most appropriate?
- Hydrocortisone and salt tablets
- Hydrocortisone and fludrocortisone
- Hydrocortisone and spironolactone
- Hydrocortisone and testosterone
- Hydrocortisone and potassium supplements
Answer:Hydrocortisone and fludrocortisone
Addison’s disease results in autoimmune destruction of the adrenal cortex. Hydrocortisone and fludrocortisone are the respective pharmacological equivalents of cortisol and aldosterone. Adrenal androgen replacement is unnecessary in males, due to testicular production of androgens (testosterone)
- However it depends on the main symptoms of the patients