In healthy patients, the lactate in lactated Ringer solution

In healthy patients, the lactate in lactated Ringer solution

  1. Causes a lactic acidosis

  2. Is converted to bicarbonate by the liver

  3. Is rapidly bound by albumin

  4. Causes a hyperchloremic metabolic acidosis

explanation

In healthy patients the lactate in lactated Ringers solution is rapidly converted to bicarbonate by the liver and does not cause a lactic acidosis. Administration of a large volume of normal saline can cause a hyperchloremic metabolic acidosis. Lactate is not bound by albumin.