In healthy patients, the lactate in lactated Ringer solution
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Causes a lactic acidosis
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Is converted to bicarbonate by the liver
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Is rapidly bound by albumin
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Causes a hyperchloremic metabolic acidosis
explanation
In healthy patients the lactate in lactated Ringers solution is rapidly converted to bicarbonate by the liver and does not cause a lactic acidosis. Administration of a large volume of normal saline can cause a hyperchloremic metabolic acidosis. Lactate is not bound by albumin.