Innovative technique converts white fat to brown fat
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Increasing healthy brown fat might help weight management and reduce symptoms of diabetes.
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Engineers have developed a simple, innovative method to directly convert white fat to brown fat outside the body and then reimplant it in a patient.
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The technique uses fat-grafting procedures commonly performed by plastic surgeons, in which fat is harvested from under the skin and then retransplanted into the same patient for cosmetic or reconstructive purposes.
Nicole R. Blumenfeld, Hwan June Kang, Anna Fenzl, Ziwei Song, Janice J. Chung, Ranjodh Singh, Roshawn Johnson, Ayse Karakecili, Jun B. Feranil, Ninna S. Rossen, Vivian Zhang, Sahir Jaggi, Bret McCarty, Steven Bessler, Gary J. Schwartz, Robert Grant, Judith Korner, Florian W. Kiefer, Brian M. Gillette, Samuel K. Sia. A direct tissue-grafting approach to increasing endogenous brown fat. Scientific Reports, 2018; 8 (1) DOI: 10.1038/s41598-018-25866-y