Kawasaki disease (mucocutaneous lymph node syndrome)

Kawasaki disease (mucocutaneous lymph node syndrome)

• Almost all cases occur in children age <5 years (incidence is greatest among children of East Asian ethnicity)

✔️ clinical diagnosis:-

Fever for >5 consecutive days (minimally responsive to antipyretics)

4 of the following 5 findings:

(1. )Conjunctivitis: bilateral, nonexudative, spares limbus

(2. )Oral mucosal changes: erythema, fissured lips, “strawberry tongue”

(3. )Rash

(4.) Extremity changes: erythema, edema, desquamation of the hands and feet, usually the last manifestation

(5. )Cervical lymphadenopathy: >1.5 cm, usually unilateral, least consistent finding (<25%-50% of patients)

Supporting lab findings in patients with atypical presentation can include the following:

  • ⬆️CRP , ⬆️ESR

  • Leukocytosis with neutrophilia

  • ⬆️PC (Reactive thrombocytosis)

  • Sterile pyuria on urinalysis


•Aspirin plus IVIG

Although KD is usually self-limited, treatment with aspirin and IVIG should be started within 10 days of fever onset to prevent cardiac complications.

✅ Baseline echocardiography (in all patients with suspected KD) and repeated 6-8 weeks later to monitor complications.


🛑Coronary artery aneurysms ( ~20% of untreated patients)

🛑Myocardial infarction & ischemia.