New type 1 diabetes therapy shows promise for long-term reversal in both humans, dogs
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What if instead of daily insulin injections or wearing pumps, just getting a shot every few months could reverse Type 1 diabetes for you – or your dog.
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It might take ushering in healthy pancreatic cells like a Trojan horse.
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The Trojan horse, in this case, would be collagen, a protein that the body already makes for building muscles, bones, skin and blood vessels.
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A collagen formulation mixed with pancreatic cells, is the first minimally invasive therapy to successfully reverse Type 1 diabetes within 24 hours and maintain insulin independence for at least 90 days, a pre-clinical animal study shows.
Clarissa Hernandez Stephens, Kara S. Orr, Anthony J. Acton, Sarah A. Tersey, Raghavendra G. Mirmira, Robert V. Considine, Sherry L. Voytik-Harbin. In-situ type I oligomeric collagen macroencapsulation promotes islet longevity and function in vitro and in vivo. American Journal of Physiology-Endocrinology and Metabolism, 2018; DOI: 10.1152/ajpendo.00073.2018
