OFF-LABEL DERMATOLOGIC USES OF NICOTINAMIDE📢
Prophylaxis and treatment of pellagra
Autoimmune bullous dermatoses ( pemphigoid,
pemphigus,dermatitis herpetiformis, and linear IgA
dermatosis)
Bullous pemphigoid : 500 mg three times daily.start with
200–300 mg three times daily+ 500 mg tetracycline four
times daily
Dietary supplement useful in acne vulgaris :Systemic
nicotinamide+azelaic acid, folic acid, copper, and
pyridoxine
Ageing : topical niacinamide
Isoniazid-induced pellagra-like skin lesions
Hartnup disease :50–300 mg/day improves dermatologic
and neurologic manifestations
Granuloma annulare : 500 mg TID
Actinic keratosis :500 mg twice daily to prevent new Aks
Wound healing
Sunscreen :Topical niacinamide