Psoriasis vs Lichen planus (histologic findings)

Psoriasis vs Lichen planus (histologic findings)

PSORIASIS

  • acanthosis( overgrowth of the stratum spinosum) (with clubbed rete ridges),

  • keratinocyte hyperproliferation,

  • **parakeratosis **** (retention of nuclei in stratum corneum).

  • usually presents with chronic erythematous plaques with silvery scales on the extensor surfaces of the knees and elbows, scalp, or neck.

LICHEN PLANUS :

  • Chronic hyperkeratosis (thickening of stratum corneum), nooo **parakeratosis ****

  • lymphocytic infiltrates at the dermoepidermal junction**

  • thickened stratum granulosum with sawtooth rete ridges***

  • eosinophilic colloid bodies in the papillary dermis

  • pruritic, purple/pink, polygonal papules and plaques

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