Which of the following is incorrect about the clinical features of hereditary spherocytosis:
1.Gallstones
2.Severe anemia during childhood
3.Splenomegaly
4.Jaundice
Solution
Some of the clinical features of herediary spherocytosis:
It has a variable presentation,not all patients presents with severe
anemia during childhood .Severe cae present in infancy with anemia mild case present during adult life
The main clinical findings are jaundice,splenomegaly,and gallstones,Usually the anemia isnormocytic
Increase in mean corpuscular hemoglobin concentraion
On the basis of red cell morphology and osmotic fragility, a modified ,a version called the pink test diagnosis
is done