A 40-years-old female comes to dermatology clinic due to a lesion on her left foot. Examination shows subcutaneous, plaque, raised and scaly rash with well-defined margins and black dots within it. The patient mentions that she noticed that it started to appear 3 years ago, and built slowly with time. 4 years ago the patient tread accidentally on broken glass in the kitchen in her house, and she removed the stuck glass pieces by herself and did not seek any medical help for that and just used over-the-counter topical creams. Biopsy shows very prominent hyperkeratosis, atypia, intraepithelial abscess, pseudoepitheliomatous hyperplasia of the lining stratified squamous epithelium, invasion of epithelial proliferation by leucocytes and disintegration of some of the epidermal cells, and multinucleated giant cells tissues that containing fibrosis between them. It shows also pigmented, and thick-walled cells with multiple inner golden-brown septae, and no amastigotes, colloid (civatte) bodies, or koilocystic changes are detected. No nodular lesion with feeder vessels or multiple discharging sinuses are presented. The patient is type 1 diabetic and has rheumatoid arthritis. Family history shows that her brother is diagnosed with one of skin cancers. Drugs history shows that she is on steroid for rheumatoid arthritis and insulin for diabetes mellitus. Brain heart inclusion agar culture at 35-37 C degrees is negative. No visualized organisms with Ziehl–Neelsen or gram stains. The most likely diagnosis of the patient is:
A) Psoriasis
Β) Low-grade squamous cell carcinoma/ Bowen’s disease
C) Undifferentiated squamous cell carcinoma
D) Sporotrichosis
E) Chromoblastomycosis
F) Mycetoma pedis
G) Leishmaniasis
H) Cutaneous lichen planus
E-black dots on appearance, pigmented golden brown septae on biopsy, usually enters the skin by foreign body