This patient suffered from defective synthesis of which of the following structural proteins?


#1

A 25-year-old man is brought to the emergency department by his next-door neighbor after being found unconscious. The neighbor reports having last seen the man working in his yard about 4 hours earlier. No medical history is available. On physical examination, the patient has a blood pressure of 60/40 mm Hg, a pulse of 150/min, and respirations of 10/min. Despite the efforts of the emergency department staff, the man cannot be resuscitated. On autopsy, he is noted to have extremely flexible joints and skin. A number of bruises are noted on his thorax that were not present on admission. The cause of death is determined to be rupture of the abdominal aorta. This patient suffered from defective synthesis of which of the following structural proteins?

  • (A) Collagen
  • (B) Elastin
  • © Fibrillin
  • (D) Keratin
  • (E) Myosin

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