True statement about fexofenadine is :

NEET SS
#1

True statement about fexofenadine is :

    1. It undergoes high first pass metabolism in liver
    1. Terfenadine is an active metabolite of this drug
    1. It does not block cardiac K+ channels
    1. It has high affinity for central H1 receptors

0 voters

exp:

Fexofenadine is an active metabolite of terfenadine. It lacks K+ channel blocking property, therefore is devoid of ar- rhythmogenic potential. It is available as a separate second generation H1 blocking agent.