Vitamin C deficiency

Vitamin C deficiency: ( Scurvy)

Pathology : Poor osteoid formation.

Clinical features:-

  • Irritability is predominant.
  • Scorbutic Rosary - ( angular and sharp costochondral junction )

Radiological findings:-

  • White line of Frankel
  • Pelkan Spur
  • Wimberger ring sign
  • Sub periosteal hemorrhage.

Note: Irritability in scurvy is due to hampered neurotransmitter production ( conversion of dopamine to norepinephrine and tryptophan to serotonin requires vitamin c ).