Which is activated for nuclear fragmentation in apoptosis -

Which is activated for nuclear fragmentation in apoptosis -

    1. Caspases
    1. Apaf - 1
    1. Oxygen free radicals
    1. None of the above

0 voters

EXP:

  • Caspases and endonuclease cause chromatin fragmentation in apoptosis.
  • They are inactive, so first they should be activated.
  • Cytochrome ‘c’ binds with Apaf-1 and this complex activates caspases.
  • Caspases cause fragmentation of chromatin and also activate endonuclease.