Which of the following antibiotics exhibits a long postantibiotic effect that permits once-daily dosing?
B. Penicillin G.
Correct answer = A.
Aminoglycosides, including gentamicin, possess a long post-antibiotic effect, especially when given as a high dose every 24 hours. Penicillin G, clindamycin, and vancomycin have a relatively short postantibiotic effect and require frequent dosing to maintain activity