Which of the following antibiotics is considered safe to use in neonates?
A. Chloramphenicol.
B. Sulfamethoxazole/trimethoprim.
C. Tetracycline.
D. Penicillin G.
Correct answer = D.
Chloramphenicol and sulfonamides (sulfamethoxazole) can cause toxic effects in newborns due to poorly developed renal and hepatic elimination processes. Tetracycline can have effects on bone growth and
development and should be avoided in newborns and young children. Penicillin G is safe and effective in this population.