Which of the following drugs acts primarily on an intracellular receptor?
(A) abciximab
(B) dexamethasone
© insulin
(D) propranolol
(E) salmeterol
ans:
(B)Dexamethasone, a corticosteroid, combines with a cytoplasmic steroid receptor, enters the nucleus, and alters gene expression. The other agents listed (choices A, C–E) act on membrane receptors.