Which of the following is least susceptible to disinfectants and antiseptics?

Which of the following is least susceptible to disinfectants and antiseptics?

1.Spore
2.Prions
3.Protozoa
4.Fungi

sol:

Prions

a. Chemical disinfectants which can be safely applied to the skin or mucus membrane and are used to prevent infection by inhibiting the growth of bacteria are called antiseptics.

b. Prions – These infectious agents are unique in being protein in nature, devoid of DNA and RNA, and unusually resistant to physical and chemical agents such as heat, irradiation and fomentation

c. Prions are resistant to inactivation by dry heat, disinfectants like aldehydes, and radiation.