Which of the following terms best describes this morphologic response to persistent injury in the esophagus of this patient?

A 69-year-old man with a history of gastroesophageal reflux disease suffers a massive stroke and expires. The esophagus at autopsy is shown in the image. Histologic examination of the abnormal tissue shows intestine-like epithelium composed of goblet cells and surface cells similar to those of incompletely intestinalized gastric mucosa. There is no evidence of nuclear atypia. Which of the following terms best describes this morphologic response to persistent injury in the esophagus of this patient?

image

  1. Atypical hyperplasia
  2. Complex hyperplasia
  3. Glandular metaplasia
  4. Simple hyperplasia
  5. Squamous metaplasia