You prescribe sumatriptan to a patient who suffers from migraines. Which one of the following side-effects is most commonly associated with this drug?
Dystonic reactions such as oculogyric crisis
Heartburn
Tightness of the throat and chest
Constipation
Insomnia
Dr. Kasper:
Tightness of the throat and chest
Triptans
Triptans are specific 5-HT1 agonists used in the acute treatment of migraine. They are generally used first-line in combination therapy with an NSAID or paracetamol.
Prescribing points
should be taken as soon as possible after the onset of headache, rather than at onset of aura
oral, orodispersible, nasal spray and subcutaneous injections are available
Adverse effects
‘triptan sensations’ - tingling, heat, tightness (e.g. throat and chest), heaviness, pressure
Contraindications
patients with a history of, or significant risk factors for, ischaemic heart disease or cerebrovascular disease