25 year old female got accidental needle stick injury by HIV positive patient who was on regular ART since 9 years with CD4 count 480 and hep b,c negative done by ELISA method… The patient’s viral load on further examination was not detectable (0 copies)… After the prick the hand was washed thoroughly with antiseptics and also blood was squeezed from the finger a little to let more blood from the area drain… The girl was given TLE(TENOFOVIR,LAMIVUDINE AND EFAVIRENZ) regime as post exposure prophylaxis and was started within 5 hours of prick… She took the medicines for 9 days after which she developed extensive maculopapular drug Rash over the body and the medicines were stopped and steroids were started which patient took for one week… Now she is totally fine
What are the chances her getting seroconversion?
Should she continue Post exposure prophylaxis?
Any other recommendations
Undetectable generally means untransmittable.
Seroconversion usually starts after 2 weeks.
I think the risk is not high… Almost a no risk case.