A 23yo woman is being followed up 6wks after a surgical procedure to evacuate the uterus
following a miscarriage. The histology has shown changes consistent with a hydatidiform mole.
What is the single most appropriate inv in this case?
a. Abdominal US
b. Maternal karyotype
c. Paternal blood group
d. Serum B-HCG
e. Transvaginal US
Ans. The key is D. Serum β-HCG. [When you are first diagnosed with a hydatidiform mole, your hCG level will be raised. When the hydatidiform mole is treated (removed), the hCG level will usually return to a normal, non-pregnant amount and should remain so. If you develop GTN, the hCG level can remain elevated or continue to rise further. So, this blood test is a good way to check for the possible development of GTN (Gestational trophoblastic neoplasia).