A 3-day-old full-term male newborn is brought to the physician by his mother because of a 24-hour history of yellow skin. He appears healthy. Physical examination shows mild jaundice. Lab studies show a hemoglobin concentration of 17 g/dL and a total serum bilirubin concentration of 10 mg/dL, with an indirect component of 8 mg/dL. The jaundice resolves 5 days later. A deficiency of which of the following is the most likely cause of the jaundice in this patient?
- A) Erythrocyte glucose 6-phosphate dehydrogenase activity
- B) Erythrocyte pyruvate kinase activity
- C) Glutathione synthetase activity
- D ) Hepatic excretion of bilirubin
- E) Hepatic UDP-glucuronosyltransferase activity
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