A 50-year-old man complains of shortness of breath on exertion of a few months’ duration. On inspection there is an increased anteroposterior diameter of the chest, pursed lips, and dyspnea with no scleral icterus or jaundice. The patient has a 75-pack-year history of smoking. On physical examination, the patient is tachycardic and has hyperresonant lungs with decreased breath sounds. There is no evidence of hepatomegaly or liver nodules on palpation. Which of the following is the most likely diagnosis?
- (A) α1-Antitrypsin deficiency
- (B) Asthma
- © Bronchiectasis
- (D) Centriacinar emphysema
- (E) Chronic bronchitis
- (F) Panacinar emphysema
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