All enzymes are not proteins. This statement is justified by
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- All enzymes do not follow the Michaelis Menton hypothesis
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- RNAs act as ribozymes
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- Antibodies take part in the catalysis of many reactions
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- Metals are involved in attachment to enzymes and catalysts
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EXP:
Ribozymes are RNA molecules with catalytic activities, which acts upon phosphodiester bonds in RNA & cause its hydrolysis [intron splicing event]. RNAs are not protein, but meet all the classic criteria of enzyme therefore all enzymes are not protein.