All of the following are characteristic features of treatment of iron deficiency anemia with oral iron supplements, except

All of the following are characteristic
features of treatment of iron deficiency
anemia with oral iron supplements,
except
a) Bioavailability is enhanced with vitamin C
b) The proportion of iron absorbed reduces as hemoglobin
improves
c) The reticulocyte count should begin to increase in two weeks
and peak in 4 weeks this suggests good response to treatment
d) The treatment should be discontinued immediately once
hemoglobin normalizes to prevent side effects of iron
Correct Answer - D
Answer- D. The treatment should be discontinued immediately
once hemoglobin normalizes to prevent side effects of iron
The reticulocyte count begin to increase within 4-7 days after
initiation of therapy and peak at 1.5 weeks.
Typically for iron replacement therapy, up to 200mg of elemental
iron per day is given, usually as three or four iron tablets (each
containing 50-65mg elemental iron) given over the course of the
day.
A dose of 200 mg of elemental iron per day should result in
absorption of iron upto 50 mg/day. This supports a red cell
production level of 2-3 times normal in an individual with a normally
functioning marrow and appropriate erythropoietin stimulus.
As the hemoglobin level rise, erythropoietin stimulation decreases,
and the amount of iron absorbed is reduced.
The goal of therapy in individuals with iron-deficiency anemia is not
only to repair the anemia, but also to provide stores of at least 0-5-1
only to repair the anemia, but also to provide stores of at least 0-5-1
g of iron.
This sustained treatment for a period of 6-12 months after correction
of the anemia will be necessary.