●Askin’s tumor is a primitive neuroectodermal tumor (PNET) of the
thoracopulmonary region of children and young adults.
●Askin’s tumor is a subset of Ewing’s sarcoma which arises from soft tissues of
the chest wall ( most commonly paravertebral region ).
● defined by reciprocal translocation t(11:22) (q24:q12) with EWS-FLI-1 fusion
●typical small round blue cells of monomorphous appearance. ( believed to be of
neural crest origin )
● Radiography of the chest -------show classical onion-peel appearance of the
●highly malignant tumor associated with poor prognosis