Atypical antipsychotics are a class tranquilizing drugs used to treat psychiatric conditions

Atypical antipsychotics are a class tranquilizing drugs used to treat psychiatric conditions. Common indications for these drugs are the positive and negative symptoms of schizophrenia, mania, Tourette’s syndrome, bipolar disorder, OCD and depression. The mechanism of action for this drug class is not entirely understood, but it is known that there are varied effects on 5HT2, dopamine, α, and H1 receptors. These drugs have less anticholinergic and extrapyramidal side effects than their typical counterparts, but can still cause seizure, prolonged QT syndrome, agranulocytosis and weight gain. Examples of atypical antipsychotic drugs are olanzapine, clozapine, quetiapine, risperdone, aripiprazole and ziprasidone.