Characterized by increase in vaginal pH and decrease lactobacilli

normal

Clue cells are squamous epithelial cells coated with cocobacilli Gardenerella vaginalis ,mycoplasma hominis and bacteroides.
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Condition called as bacterial vaginosis, characterized by increase in vaginal pH and decrease lactobacilli.
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Normal squamous epithelial cell have distinct cell margins and lack granularity. Numerous bacteria have adhesins that promote sticking to the surfaces and also from a biofilm, hence they tend due to adhere on The surfaces leading to appearance of granularity with indistinct or stippled border termed as clue cells.
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Positive test : Amsel criteria and positive Whiff test.