Chemistry and Metabolism of Lipids

  1. Which of the following is not a simple lipid?
    a) Waxes
    b) Lanolin
    c) Fatty acid
    d) Coconut oil
  2. Which of the following is a MUFA?
    a) Palmitic acid
    b) Palmitoleic acid
    c) Elaidic cid
    d) Stearic acid
  3. The number of double bonds in Cervonic acid
    a) 2
    b) 4
    c) 6
    d) 8
  4. About alpha linolenic acid false statement is
    a) It belongs to ω3 fatty acid
    b) Decreases S Triglycerides
    c) Used in the treatment of Type II Hyperlipoproteinemia
    d) Highest content in Flax seed oil
  5. Nitrogen is NOT present in which of the following Phospholipids?
    a) Cephalin
    b) Plasmalogen
    c) Cardiolipin
    d) Lecithin
  6. Phosophlipid first isolated from cardiac muscle is
    …………………………………………………….
  7. Phospholipid important as second messengers in hormonal pathways is
    ………………………………
  8. Sphingosine + Fatty acid is ………………………………………
  9. The chemical group absent in a Ganglioside is
    a) NH2
    b) OH
    c) NANA
    d) PO4
  10. Simplest ganglioside is ……………………………………
  11. Write the enzyme defect and accumulating substance in
    Metabolism of Lipids
  12. Function of bile salt are all except
    a) Detergent action
    b) Reduces Surface tension
    c) Emulsification of lipid products
    d) Needed for absorption of short chain, medium chain and long chain fatty acid.
  13. Glycerol kinase is absent in
    a) Liver
    b) Brown Adipose tissue
    c) Kidney
    d) Skeletal Muscle
  14. Hormone sensitive Lipase is inactivated by all except
    a) Insulin
    b) PGE1
    c) Niacin
    d) Thyroxine
  15. Malonyl CoA is formed by the action of
    a) Malonyl Transacylase
    b) Acetyl CoA Carboxylase
    c) Acetyl Transacylase
    d) Enoyl reductase
  16. About FAS complex false is
    a) It a multifunctional enzyme
    b) It has 6 enzyme activity
    c) It require Biotin, Mn & NADPH
    d) Acety CoA Carboxylase is not a part of it
  17. Elongation of fatty acid occur in ……………………………………………………………
  18. Which of the following inactivate Acetyl CoA Carboxylase
    a) Insulin
    b) Acetyl CoA
    c) Citrate
    d) Acyl CoA
  19. Humans cannot insert double bond beyond ……………………………………
  20. About energetics 1 palmitic acid by beta oxidation ,false is
    a) 80 ATP from TCA Cycle
    b) 106 ATPs
    c) 4 ATPs from I1 Cycle of beta oxidation
    d) Needs 4 ATPs for activation
    10.Fasting hypoglycaemia in MCAD deficiency is due to
    a) Omega oxidation
    b) No Acetyl CoA to activate Pyruvate Cehydrogenase
    c) Lack of ATP to support gluconeogenesis
    d) Lack of Ketone bodies
  21. Enzyme that require B12 in the conversion of Propionyl CoA to Succinyl CoA is
    ………………………………
  22. About Zellweger Syndrome false is
    a) Accumulation of VLCFA in peroxisomes
    b) Lysosomal disorder
    c) Resemble Down’s Syndrome
    d) Accumulation of Pipecolic acid
  23. Organs that do not utilise ketone bodies is ………………………………………….
    14.Enzyme that utilise ketone bodies is ………………………………………………
    15.Ketone body that is excreted through lungs is …………………….
  24. Lipotropic factors are all except
    a) Tocopherol
    b) Choline
    c) Linoleic acid
    d) Zinc
  25. Causes of fatty liver are all except
    a) Starvation
    b) PEM
    c) Lack of apolipoprotein
    d) Feeding of low fat diet
  26. Rate limiting step of bile acid synthesis ……………………………………………………
  27. Specialised products from cholesterol are all except
    a) Cholic acid
    b) Cholecalciferol
    c) Chenodeoxycholic acid
    d) Progesterone
  28. About regulation cholesterol synthesis false statement is ………………………………
    a) Cholesterol repress transcription of HMG CoA Reductase
    b) Insulin and Glucagon has a dominant role in regulation
    c) Phosphorylation inhibit HMG CoA Reductase
    d) Glucocorticoids inhibit cholesterol synthesis