Cinaguat is used in chronic or acute chf?

cinaguat is used in chronic or acute chf?

Cinaciguat is primarily used in the context of acute heart failure (acute decompensated heart failure). It is a soluble guanylate cyclase (sGC) activator that works by enhancing the nitric oxide-sGC-cGMP signaling pathway, leading to vasodilation and improved cardiac function.

Usage Context:

  • Acute Heart Failure (Acute Decompensated Heart Failure): Cinaciguat has been investigated for its potential benefits in acute heart failure, where rapid improvement in cardiac output and reduction in symptoms are needed.

Not Typically Used for:

  • Chronic Heart Failure: Chronic heart failure management typically involves medications such as ACE inhibitors, ARBs, beta-blockers, diuretics, and mineralocorticoid receptor antagonists. Cinaciguat is not commonly used in the chronic setting.


Cinaciguat is used for acute heart failure rather than chronic heart failure.