Congenital rubella
of transmission significantly (spiramycin)
Infants are treated with pyrimethamine, sulfadiazide, and leucovorin.
Classic findings when maternal infection occurs in first 8 weeks’ gestation.
Findings
Blueberry muffin spots (extramedullary hematopoiesis),
thrombocytopenia
Cardiac—PDA, peripheral pulmonary artery stenosis
Eye—cataracts
Congenital hearing loss
Thrombocytopenia
Hepatosplenomegaly
Outcomes
Hearing loss
Persistent growth retardation
Microcephaly
Cytomegalovirus (CMV)
Herpes simplex
Mental and motor retardation