Dihydroergotamine differs from ergotamine in following respect

Dihydroergotamine differs from ergotamine in following respect :

    1. It is a more potent oxytocic
    1. It has antiemetic property
    1. It has high oral bioavailability
    1. It is more potent a adrenergic blocker and less potent vasoconstrictor

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EXP:

Hydrogenation of ergot alkaloids decrease their vasoconstrictor action and increase the α-blocking activity.