DOXORUBICIN INDUCED CARDIOTOXICITY
Doxorubicin is an anti cancer drug which produces cardiotoxicity as side effect
Clinical features
Acute presentation with hypotension, arrhythmias, bundle branch block, ST changes
Delayed presentation with features of congestive cardiac failure
Pathology
Development of cardiac toxicity is due to cardiomyopathy
Risk increases beyond doses of 550mg/m2